Inhibitors | Comment | Organism | Structure |
---|---|---|---|
oxalomalic acid | inhibition of aconitase activity, leading to inhibition of L-glutamate production, L-cystine uptake, and decrease in glutathione concentration in lens epithelial cells and retinal pigment epithelial cells | Canis lupus familiaris |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | iron-induced increase in L-glutamate availability increases via the aconitase pathway L-cystine uptake, with subsequent increases in glutathione levels | Canis lupus familiaris |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
eye | - |
Canis lupus familiaris | - |
lens epithelium | - |
Canis lupus familiaris | - |
retinal pigment epithelium | - |
Canis lupus familiaris | - |