Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hydrogen peroxide | inhibits enzyme activity in cell-free extracts | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | aconitase is phosphorylated on serine residues. Increase in extensor digitorum longus muscle enzyme activity upon repeated contraction is inhibited by cyclosporin A, an inhibitor of the protein phosphates calcineurin | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
extensor digitorum longus | repeated contractions increase aconitase activity by 50%. Increase is not accompanied by increase in aconitase protein, but is markedly inhibited by cyclosporin A | Mus musculus | - |
skeletal muscle | muscle exercise does not affect aconitase activity despite increased oxidative stress | Homo sapiens | - |
soleus | repeated contractionsdo not alter aconitase activity | Mus musculus | - |