Activating Compound | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | - |
Saccharomyces cerevisiae | |
S-adenosyl-L-methionine | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-serine + L-homocysteine | Aeropyrum pernix | - |
L-cystathionine + H2O | - |
? | |
L-serine + L-homocysteine | Saccharomyces cerevisiae | - |
L-cystathionine + H2O | - |
? | |
L-serine + L-homocysteine | Homo sapiens | - |
L-cystathionine + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aeropyrum pernix | Q9YCN5 | cystathionine beta-synthase | - |
Homo sapiens | P35520 | - |
- |
Saccharomyces cerevisiae | P32582 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-serine + L-homocysteine | - |
Aeropyrum pernix | L-cystathionine + H2O | - |
? | |
L-serine + L-homocysteine | - |
Saccharomyces cerevisiae | L-cystathionine + H2O | - |
? | |
L-serine + L-homocysteine | - |
Homo sapiens | L-cystathionine + H2O | - |
? | |
additional information | O-acetylserine sulfhydrylase isozyme A, OASSAp, EC 2.5.1.65, exhibits both O-acetylserine sulfhydrylase and cystathionine beta-synthase activities | Aeropyrum pernix | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
multimer | - |
Saccharomyces cerevisiae |
multimer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
CBS | - |
Aeropyrum pernix |
CBS | - |
Saccharomyces cerevisiae |
CBS | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Saccharomyces cerevisiae | |
heme | - |
Homo sapiens | |
pyridoxal 5'-phosphate | - |
Aeropyrum pernix | |
pyridoxal 5'-phosphate | - |
Saccharomyces cerevisiae | |
pyridoxal 5'-phosphate | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | CBS is involved in the cysteine pathway of bacteria and plants, overview | Saccharomyces cerevisiae |
metabolism | CBS is involved in the cysteine pathway of bacteria and plants, overview | Homo sapiens |
metabolism | cystathionine beta-synthase is involved in the cysteine pathway of bacteria and plants, overview | Aeropyrum pernix |