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Literature summary for 4.2.1.22 extracted from
- Tumor necrosis factor-a-induced targeted proteolysis of cystathionine beta-xynthase modulates redox homeostasis (2003), J. Biol. Chem., 278, 16802-16808.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| tumor necrosis factor-alpha | leads to cleavage of the enzyme to a truncated form and therefore increases the activity, 50% increase of activity after treatment of HepG2 cells for 16 h | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Serine + homocysteine | - |
Homo sapiens | Cystathionine + H2O | - |
r |  |
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