Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion of 70 N-terminal residues results in a heme-free protein retaining 20% activity, additional deletion of 151 C-terminal residues results in an inactive enzyme, deletion of 8 C-terminal residues results in increased enzyme activity and abolishes any further activation by S-adenosyl-L-methionine | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
full length enzyme exhibits a strong tendency toward aggregation during the course of purification as well as in the purified state | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Serine + homocysteine | - |
Homo sapiens | Cystathionine + H2O | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | SDS-PAGE | Homo sapiens |