Literature summary for 4.2.1.22 extracted from

Gallagher, P.M.; Naughten, E.; Hanson, N.Q.; Schwichtenberg, K.; Bignell, M.; Yuan, M.; Ward, P.; Yap, S.; Whitehead, A.S.; Tsai, M.Y.
Characterization of mutations in the cystathionine beta-synthase gene in irish patients with homocystinuria (1998), Mol. Genet. Metab., 65, 298-302.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-Serine + homocysteine	Homo sapiens	reduced activity of EC 4.2.1.22 in patients with homocystinuria due to mutations in the CBS gene	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-Serine + homocysteine	reduced activity of EC 4.2.1.22 in patients with homocystinuria due to mutations in the CBS gene	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)