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Literature summary for 4.2.1.20 extracted from

  • Goss, R.J.; Newill, P.L.
    A convenient enzymatic synthesis of L-halotryptophans (2006), Chem. Commun. (Camb. ), 2006, 4924-4925.
    View publication on PubMed
Search for more literature for 4.2.1.20

Cloned(Commentary)

Cloned (Comment) Organism
Escherichia coli pretransformed with pSTB7, a high copy number plasmid expressing tryptophan synthase from Salmonella enterica, is commercially available (ATCC 37845) Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-(indol-3-yl)glycerol 3-phosphate + L-serine Salmonella enterica
-
 L-tryptophan + D-glyceraldehyde 3-phosphate + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell lysate lysate Salmonella enterica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-(indol-3-yl)glycerol 3-phosphate + L-serine
-
 Salmonella enterica L-tryptophan + D-glyceraldehyde 3-phosphate + H2O
-
 ?
L-serine + 2-methylindole
-
 Salmonella enterica 2-methyltryptophan + H2O
-
 ?
L-serine + 4-bromoindole
-
 Salmonella enterica 4-bromotryptophan + H2O
-
 ?
L-serine + 4-methylindole
-
 Salmonella enterica 4-methyltryptophan + H2O
-
 ?
L-serine + 5-bromoindole
-
 Salmonella enterica 5-bromotryptophan + H2O
-
 ?
L-serine + 5-chloroindole
-
 Salmonella enterica 5-chlorotryptophan + H2O
-
 ?
L-serine + 5-fluoroindole
-
 Salmonella enterica 5-fluorotryptophan + H2O
-
 ?
L-serine + 5-methylindole
-
 Salmonella enterica 5-methyltryptophan + H2O
-
 ?
L-serine + 6-bromoindole
-
 Salmonella enterica 6-bromotryptophan + H2O
-
 ?
L-serine + 6-chloroindole
-
 Salmonella enterica 6-chlorotryptophan + H2O
-
 ?
L-serine + 6-fluoroindole
-
 Salmonella enterica 6-fluorotryptophan + H2O
-
 ?
L-serine + 6-methylindole
-
 Salmonella enterica 6-methyltryptophan + H2O
-
 ?
L-serine + 7-bromoindole
-
 Salmonella enterica 7-bromotryptophan + H2O
-
 ?
L-serine + 7-chloroindole
-
 Salmonella enterica 7-chlorotryptophan + H2O
-
 ?
L-serine + 7-fluoroindole
-
 Salmonella enterica 7-fluorotryptophan + H2O
-
 ?
L-serine + 7-methylindole
-
 Salmonella enterica 7-methyltryptophan + H2O
-
 ?
L-serine + indole
-
 Salmonella enterica L-tryptophan + H2O
-
 ?
additional information one-step synthesis of fluoro, chloro, bromo and methyltryptophans using a readily prepared bacterial cell lysate Salmonella enterica ?
-
 ?

Synonyms

Synonyms Comment Organism
tryptophan synthase
-
 Salmonella enterica