Literature summary for 4.2.1.17 extracted from

Liu, X.; Feng, R.; Du, L.
The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells (2010), FEBS Lett., 584, 3185-3192.

Search for more literature for 4.2.1.17

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MCF-7 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ECHS1	-	Homo sapiens
enoyl-CoA hydratase short chain 1	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	ECHS1 is downregulated by 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, i.e. PP2, that induces apoptosis in breast cancer MCF-7 cells	down

General Information

General Information	Comment	Organism
additional information	key role of ECHS1 and PRDX3 in regulation of 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, PP2, -induced apoptosis, downregulation of ECHS1 and PRDX3 potentiates PP2-induced apoptosis in MCF-7 cells, overview	Homo sapiens

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Release 2023.1 (January 2023)