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Literature summary for 4.2.1.17 extracted from
- Bacillus subtilis fadB (ysiB) gene encodes an enoyl-CoA hydratase (2011), Ann. Microbiol., 61, 371-374.
No PubMed abstract available
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of recombinant His6-tagged FadB from pET21b-fadBBs in Escherichia coli strain BL21(DE3) | Bacillus subtilis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Bacillus subtilis | stereoselectivity of 2-enoyl-CoA dehydratase | ? | - |
? |  |
| additional information | Bacillus subtilis 168 | stereoselectivity of 2-enoyl-CoA dehydratase | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
gene fadB or ysiB | - |
| Bacillus subtilis 168 | - |
gene fadB or ysiB | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | stereoselectivity of 2-enoyl-CoA dehydratase | Bacillus subtilis | ? | - |
? | |
| additional information | stereoselectivity of 2-enoyl-CoA dehydratase | Bacillus subtilis 168 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FadRBs | - |
Bacillus subtilis |
| YsiA | - |
Bacillus subtilis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Bacillus subtilis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Bacillus subtilis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | FadRBs or YsiA is a transcriptional regulatory protein which negatively regulates the expression of beta-oxidation genes including those belonging to the lcfA operon, including fadRBs or ysiA. FadBBs is active in the hydratation of crotonyl-CoA, supporting the possibility of its direct involvement in the beta-oxidation pathway | Bacillus subtilis |
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Release 2023.1 (January 2023)
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