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Literature summary for 4.2.1.161 extracted from

  • Yang, Y.; Yatsunami, R.; Ando, A.; Miyoko, N.; Fukui, T.; Takaichi, S.; Nakamura, S.
    Complete biosynthetic pathway of the C50 carotenoid bacterioruberin from lycopene in the extremely halophilic archaeon Haloarcula japonica (2015), J. Bacteriol., 197, 1614-1623.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.161

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
bisanhydrobacterioruberin + 2 H2O Haloarcula japonica the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin. It introduced hydroxyl groups to C3'' and C3''' of bisanhydrobacterioruberin to generate bacterioruberin bacterioruberin
-
 ?
bisanhydrobacterioruberin + H2O Haloarcula japonica the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin monoanhydrobacterioruberin
-
 ?
monoanhydrobacterioruberin + H2O Haloarcula japonica the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin bacterioruberin
-
 ?

Organism

Organism UniProt Comment Textmining
Haloarcula japonica A0A0A1GNF2
-
-

Reaction

Reaction Comment Organism Reaction ID
bacterioruberin = bisanhydrobacterioruberin + 2 H2O (overall reaction) Haloarcula japonica
a
bacterioruberin = monoanhydrobacterioruberin + H2O (1a) Haloarcula japonica
a
monoanhydrobacterioruberin = bisanhydrobacterioruberin + H2O (1b) Haloarcula japonica
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bisanhydrobacterioruberin + 2 H2O the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin. It introduced hydroxyl groups to C3'' and C3''' of bisanhydrobacterioruberin to generate bacterioruberin Haloarcula japonica bacterioruberin
-
 ?
bisanhydrobacterioruberin + 2 H2O the enzyme introduced hydroxyl groups to C3'' and C3''' of bisanhydrobacterioruberin to generate bacterioruberin Haloarcula japonica bacterioruberin
-
 ?
bisanhydrobacterioruberin + H2O
-
 Haloarcula japonica monoanhydrobacterioruberin
-
 ?
bisanhydrobacterioruberin + H2O the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin Haloarcula japonica monoanhydrobacterioruberin
-
 ?
monoanhydrobacterioruberin + H2O
-
 Haloarcula japonica bacterioruberin
-
 ?
monoanhydrobacterioruberin + H2O the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin Haloarcula japonica bacterioruberin
-
 ?

Synonyms

Synonyms Comment Organism
c0505
-
 Haloarcula japonica
CruF
-
 Haloarcula japonica

General Information

General Information Comment Organism
malfunction the deletion mutant strain DELTAc0505 shows the same growth rate as wild-type strain. The main cartotenoid products of the mutant strain are monoanhydrobacterioruberin and bisanhydrobacterioruberin. When plasmid pJc0505 containing the intact c0505 gene is introduced into the DELTAc0507 strain, the transformant restores the production of bacterioruberin Haloarcula japonica
metabolism the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin Haloarcula japonica