Literature summary for 4.2.1.159 extracted from

Aguirrezabalaga, I.; Olano, C.; Allende, N.; Rodriguez, L.; Brana, A.; Mendez, C.; Salas, J.
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus (2000), Antimicrob. Agents Chemother., 44, 1266-1275.

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Application

Application	Comment	Organism
synthesis	construction of a Streptomyces albus strain harboring the oleG2 glycosyltransferase gene and transformation with plasmid constructs containing a set of genes proposed to be required for the biosynthesis of dTDP-L-olivose and dTDP-L-oleandrose, respectively. Incubation of these strains with the erythromycin aglycon (erythronolide B) gives rise to two new glycosylated compounds, identified as L-3-O-olivosyl- and L-3-O-oleandrosyl-erythronolide B. Plasmid constructs pOLV and pOLE containing the oleW, oleV, oleL, oleS, oleE, and oleU genes and the 5' end of oleNI encode all enzyme activities required for the biosynthesis of these two 2,6-dideoxysugars	Streptomyces antibioticus

Cloned(Commentary)

Cloned (Comment)	Organism
-	Streptomyces antibioticus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces antibioticus	Q9RR31	-	-

Synonyms

Synonyms	Comment	Organism
oleV	-	Streptomyces antibioticus

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Release 2023.1 (January 2023)