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Literature summary for 4.2.1.155 extracted from

  • Reisch, C.R.; Stoudemayer, M.J.; Varaljay, V.A.; Amster, I.J.; Moran, M.A.; Whitman, W.B.
    Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria (2011), Nature, 473, 208-211.
    View publication on PubMed
Search for more literature for 4.2.1.155

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-(methylthio)acryloyl-CoA + 2 H2O Ruegeria pomeroyi the enzyme involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton acetaldehyde + methanethiol + CoA + CO2
-
 ?
3-(methylthio)acryloyl-CoA + 2 H2O Ruegeria pomeroyi DSM 15171 the enzyme involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton acetaldehyde + methanethiol + CoA + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Ruegeria pomeroyi Q5LLW6
-
-
Ruegeria pomeroyi DSM 15171 Q5LLW6
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Ruegeria pomeroyi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(methylthio)acryloyl-CoA + 2 H2O the enzyme involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton Ruegeria pomeroyi acetaldehyde + methanethiol + CoA + CO2
-
 ?
3-(methylthio)acryloyl-CoA + 2 H2O 3-(methylthio)acryloyl-CoA i.e. 3-(methylthio)prop-2-enoyl-CoA Ruegeria pomeroyi acetaldehyde + methanethiol + CoA + CO2
-
 ?
3-(methylthio)acryloyl-CoA + 2 H2O the enzyme involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton Ruegeria pomeroyi DSM 15171 acetaldehyde + methanethiol + CoA + CO2
-
 ?
3-(methylthio)acryloyl-CoA + 2 H2O 3-(methylthio)acryloyl-CoA i.e. 3-(methylthio)prop-2-enoyl-CoA Ruegeria pomeroyi DSM 15171 acetaldehyde + methanethiol + CoA + CO2
-
 ?

Synonyms

Synonyms Comment Organism
MTA-CoA hydratase
-
 Ruegeria pomeroyi
SPO3805 locus name Ruegeria pomeroyi

General Information

General Information Comment Organism
malfunction a dmdD (SPO3805::tet) mutant fails to grow with 3-methylmercaptopropionate, and growth on dimethylsulphoniopropionate is severely inhibited Ruegeria pomeroyi
metabolism the enzyme is involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton. The transcript for dmdD increases during growth on methylmercaptopropionate or dimethylsulphoniopropionate Ruegeria pomeroyi