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Literature summary for 4.2.1.135 extracted from

  • Mostafavi, A.Z.; Troutman, J.M.
    Biosynthetic assembly of the Bacteroides fragilis capsular polysaccharide A precursor bactoprenyl diphosphate-linked acetamido-4-amino-6-deoxygalactopyranose (2013), Biochemistry, 52, 1939-1949.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.135

Application

Application Comment Organism
synthesis sugar capsule capsular polysaccharide A (CPSA), which coats the surface of the mammalian symbiont Bacteroides fragilis, is a key mediator of mammalian immune system development, the enzyme, coupled to a Bacteroides fragilis-encoded aminotransferase (WcfR), is used in sythetic construction system for CPSA for synthesis of the rare stereoconfiguration sugar acetamido-4-amino-6-deoxygalactopyranose in a two-step coupled reaction with WcfR, overview Campylobacter jejuni

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PglF catalyzes the formation of a UDP-4-oxo sugar with the appropriate stereochemistry at position 5'' from UDP-GlcNAc. Sugar capsule capsular polysaccharide A (CPSA), which coats the surface of the mammalian symbiont Bacteroides fragilis, is a key mediator of mammalian immune system development, the enzyme, coupled to a Bacteroides fragilis-encoded aminotransferase (WcfR), is used in sythetic construction system for CPSA for synthesis of the rare stereoconfiguration sugar acetamido-4-amino-6-deoxygalactopyranose in a two-step coupled reaction with WcfR, overview Campylobacter jejuni ?
-
 ?

Synonyms

Synonyms Comment Organism
PglF
-
 Campylobacter jejuni

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28
-
 assay at Campylobacter jejuni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Campylobacter jejuni