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Literature summary for 4.2.1.127 extracted from

  • Petasch, J.; Disch, E.M.; Markert, S.; Becher, D.; Schweder, T.; Huettel, B.; Reinhardt, R.; Harder, J.
    The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen (2014), BMC Microbiol., 14, 164.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information generation of an in-frame deletion mutants Castellaniella defragrans DELTAldi Castellaniella defragrans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-myrcene + H2O Castellaniella defragrans
-
(3S)-linalool
-
?
beta-myrcene + H2O Castellaniella defragrans 65Phen
-
(3S)-linalool
-
?

Organism

Organism UniProt Comment Textmining
Castellaniella defragrans E1XUJ2 i.e. Alcaligenes defragrans, gene ldi
-
Castellaniella defragrans 65Phen E1XUJ2 i.e. Alcaligenes defragrans, gene ldi
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information proteome analysis of cells grown on acetate and alpha-phellandrene by 2D-SDS-PAGE and LC-ESI-MS/MS of whole-cell homogenate and membrane protein-enriched fraction, overview Castellaniella defragrans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-myrcene + H2O
-
Castellaniella defragrans (3S)-linalool
-
?
beta-myrcene + H2O
-
Castellaniella defragrans 65Phen (3S)-linalool
-
?

Synonyms

Synonyms Comment Organism
LDI
-
Castellaniella defragrans
ldi/LDI
-
Castellaniella defragrans
linalool dehydratase-isomerase
-
Castellaniella defragrans

Expression

Organism Comment Expression
Castellaniella defragrans proteome analysis of cells grown on acetate and alpha-phellandrene by 2D-SDS-PAGE and LC-ESI-MS/MS of whole-cell homogenate and membrane protein-enriched fraction, overview additional information

General Information

General Information Comment Organism
malfunction an in-frame deletion mutant with an inactivated ldi gene shows no growth with the acyclic beta-myrcene, but grows like the wild type on limonene or alpha-phellandrene Castellaniella defragrans
metabolism beta-myrcene is enantiospecifically hydrated to (S)-(+)-linalool and further isomerized to geraniol by the linalool dehydrataseisomerase Castellaniella defragrans