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Literature summary for 4.2.1.125 extracted from

  • Kim, O.T.; Kim, S.H.; Ohyama, K.; Muranaka, T.; Choi, Y.E.; Lee, H.Y.; Kim, M.Y.; Hwang, B.
    Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase (2010), Plant Cell Rep., 29, 403-411.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Centella asiatica
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Source Tissue

Source Tissue Comment Organism Textmining
hairy root
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Centella asiatica
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General Information

General Information Comment Organism
physiological function Centella asiatica hairy roots overexpressing ginseng farnesyl diphosphate synthase show higher levels of dammarenediol synthase and cycloartenol synthase mRNA when compared with the controls. No differences are detected in expression of the squalene synthase gene. The upregulation of dammarenediol synthase transcripts suggests that FPS may result in alterations in triterpene biosynthesis capacity. Squalene contents in the T17, T24, and T27 lines increase to 1.1-, 1.3- and 1.5fold those in the controls, respectively. The total sterol contents in the T24 line are approximately three times higher than those of the controls Centella asiatica