Literature summary for 4.2.1.120 extracted from

Martins, B.M.; Dobbek, H.; Cinkaya, I.; Buckel, W.; Messerschmidt, A.
Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe-4S] cluster and flavin (2004), Proc. Natl. Acad. Sci. USA, 101, 15645-15649.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
to 1.6 A resolution. A [4Fe-4S]2+ cluster, coordinated by three cysteine and one histidine residues, is located 7 A from the Re-side of a flavin adenine dinucleotide moiety. The substrate can be bound between the [4Fe-4S]2+ cluster and the FAD with both cofactors contributing to its radical activation and catalytic conversio	Clostridium aminobutyricum

Organism

Organism	UniProt	Comment	Textmining
Clostridium aminobutyricum	P55792	-	-

Cofactor

Cofactor	Comment	Organism	Structure
4Fe-4S-center	a [4Fe-4S]2+ cluster, coordinated by three cysteine and one histidine residues, is located 7 A from the Re-side of a flavin adenine dinucleotide moiety	Clostridium aminobutyricum
FAD	a [4Fe-4S]2+cluster, coordinated by three cysteine and one histidine residues, is located 7 A from the Re-side of a flavin adenine dinucleotide moiety	Clostridium aminobutyricum

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Release 2023.1 (January 2023)