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Literature summary for 4.2.1.11 extracted from

  • Brewer, J.M.; McKinnon, J.S.; Phillips, R.S.
    Stopped-flow studies of the reaction of D-tartronate semialdehyde-2-phosphate with human neuronal enolase and yeast enolase 1 (2010), FEBS Lett., 584, 979-983.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Mg2+ Mg2+ is inhibitory at 30 mM to the physiological reaction, but not to the reaction with D-tartronate semialdehyde phosphate Homo sapiens
Mg2+ Mg2+ is inhibitory at 30 mM to the physiological reaction, but not to the reaction with D-tartronate semialdehyde phosphate Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for activity Homo sapiens
Mg2+ required for activity Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phospho-D-glycerate Homo sapiens
-
phosphoenolpyruvate + H2O
-
r
2-phospho-D-glycerate Saccharomyces cerevisiae
-
phosphoenolpyruvate + H2O
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens
-
Saccharomyces cerevisiae

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
Homo sapiens phosphoenolpyruvate + H2O
-
r
2-phospho-D-glycerate
-
Saccharomyces cerevisiae phosphoenolpyruvate + H2O
-
r
D-tartronate semialdehyde phosphate slowly-reacting strongly bound chromophoric substrate Homo sapiens ?
-
?
D-tartronate semialdehyde phosphate slowly-reacting strongly bound chromophoric substrate Saccharomyces cerevisiae ?
-
?

Synonyms

Synonyms Comment Organism
2-phospho-D-glycerate hydrolyase
-
Homo sapiens
2-phospho-D-glycerate hydrolyase
-
Saccharomyces cerevisiae
enolase 1
-
Saccharomyces cerevisiae
enolase gamma
-
Homo sapiens
neuronal enolase
-
Homo sapiens