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Literature summary for 4.2.1.106 extracted from

  • Wells, J.E.; Hylemon, P.B.
    Identification and characterization of a bile acid 7alpha-dehydroxylation operon in Clostridium sp. strain TO-931, a highly active 7alpha-dehydroxylating strain isolated from human feces (2000), Appl. Environ. Microbiol., 66, 1107-1113.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
cloning of bai operon containing BaiE gene coding for bile acid 7alpha-dehydratase Clostridium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7alpha,12alpha-dihydroxy-3-oxochol-4-enoate Clostridium sp.
-
12alpha-hydroxy-3-oxocholate-4,6-dienoate
-
?
7alpha,12alpha-dihydroxy-3-oxochol-4-enoate Clostridium sp. TO-931
-
12alpha-hydroxy-3-oxocholate-4,6-dienoate
-
?

Organism

Organism UniProt Comment Textmining
Clostridium sp.
-
-
-
Clostridium sp. TO-931
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7alpha,12alpha-dihydroxy-3-oxochol-4-enoate
-
Clostridium sp. 12alpha-hydroxy-3-oxocholate-4,6-dienoate
-
?
7alpha,12alpha-dihydroxy-3-oxochol-4-enoate
-
Clostridium sp. TO-931 12alpha-hydroxy-3-oxocholate-4,6-dienoate
-
?