Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Aspergillus nidulans | |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Streptomyces coelicolor | |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
additional information | Ki-values for (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid and (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid are above 25 mM | Salmonella enterica subsp. enterica serovar Typhimurium |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.018 | - |
dehydroquinate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
0.064 | - |
dehydroquinate | - |
Mycobacterium tuberculosis | |
0.15 | - |
dehydroquinate | - |
Aspergillus nidulans | |
0.65 | - |
dehydroquinate | - |
Streptomyces coelicolor |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Mycobacterium tuberculosis | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Streptomyces coelicolor | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-dehydroquinate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 3-dehydroshikimate + H2O | - |
? | |
3-dehydroquinate | - |
Aspergillus nidulans | 3-dehydroshikimate + H2O | - |
? | |
3-dehydroquinate | - |
Mycobacterium tuberculosis | 3-dehydroshikimate + H2O | - |
? | |
3-dehydroquinate | - |
Streptomyces coelicolor | 3-dehydroshikimate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Type I dehydroquinase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Type II dehydroquinase | - |
Aspergillus nidulans |
Type II dehydroquinase | - |
Mycobacterium tuberculosis |
Type II dehydroquinase | - |
Streptomyces coelicolor |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki-values for (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid and (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid are above 25 mM | Salmonella enterica subsp. enterica serovar Typhimurium | |
0.015 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
0.02 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
0.03 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Streptomyces coelicolor | |
0.06 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Aspergillus nidulans | |
0.2 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
0.5 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
0.6 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
0.7 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
1.2 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
1.5 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
2.2 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
2.5 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
3 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
4.5 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium |