Application | Comment | Organism |
---|---|---|
medicine | CA IX is a marker of tumor hypoxia and a prognostic factor in several human cancers, inhibition of this enzyme shows antitumor activity both in vitro and in vivo | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
using the baculovirusinsect cell expression system | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapor diffusion method, using 0.4 M NH4H2PO4, 0.1 M sodium citrate, pH 5.0 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Homo sapiens | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16790 | - |
- |
Purification (Comment) | Organism |
---|---|
Superdex 200 gel filtration and Superdex 75 gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CO2 + H2O | - |
Homo sapiens | H2CO3 | - |
r |
Synonyms | Comment | Organism |
---|---|---|
CA IX | - |
Homo sapiens |
carbonic anhydrase IX | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | CA IX is involved in solid tumor acidification | Homo sapiens |