Literature summary for 4.2.1.1 extracted from

Elder, I.; Han, S.; Tu, C.; Steele, H.; Laipis, P.J.; Viola, R.E.; Silverman, D.N.
Activation of carbonic anhydrase II by active-site incorporation of histidine analogs (2004), Arch. Biochem. Biophys., 412, 283-289.

No PubMed abstract available

Search for more literature for 4.2.1.1

Cloned(Commentary)

Cloned (Comment)	Organism
cloned and overexpressed	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
F131C	site-directed mutant	Homo sapiens
H64A	site-directed mutant	Homo sapiens
I91C	site-directed mutant	Homo sapiens
N62C	site-directed mutant	Homo sapiens
W5C	site-directed mutant	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	zinc bound water molecule of the enzyme	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
H2CO3	Homo sapiens	-	CO2 + H2O	-	r

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
H2CO3	-	Homo sapiens	CO2 + H2O	-	r

Synonyms

Synonyms	Comment	Organism
HC II	-	Homo sapiens
human carbonic anhydrase II	-	Homo sapiens

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Release 2023.1 (January 2023)