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Literature summary for 4.1.99.3 extracted from
- More than a repair enzyme: Aspergillus nidulans photolyase-like CryA is a regulator of sexual development (2008), Mol. Biol. Cell, 19, 3254-3262.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in DANN-repair deficient Escherichia coli strains DH5alpha and MACH-1 | Aspergillus nidulans |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Aspergillus nidulans | 5634 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Aspergillus nidulans | CryA can repair DNA upon exposure to UVA light similar to other photolyase proteins, CryA represses sexual development under UVA350-370 nm light and exhibits a regulatory function during light-dependent development and DNA repair activity, in the wild type strain mechanisms such as excision repair mask the DNA photolyase activity of CryA | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus nidulans | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mycelium | - |
Aspergillus nidulans | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cyclobutadipyrimidine in DNA | - |
Aspergillus nidulans | pyrimidine residues in DNA | - |
? | |
| additional information | CryA can repair DNA upon exposure to UVA light similar to other photolyase proteins, CryA represses sexual development under UVA350-370 nm light and exhibits a regulatory function during light-dependent development and DNA repair activity, in the wild type strain mechanisms such as excision repair mask the DNA photolyase activity of CryA | Aspergillus nidulans | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CPD photolyase | - |
Aspergillus nidulans |
| CryA | the CryA sequence is located within the group of class I CPD photolyases | Aspergillus nidulans |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FADH2 | - |
Aspergillus nidulans | |
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