Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | Vitreoscilla hemoglobin positive strains (vgb+ strains) have substantially higher TPL activity than the respective wild-type hosts or the strains bearing a comparable plasmid without vgb (the vgb- strains) | Pantoea agglomerans | |
additional information | Vitreoscilla hemoglobin positive strains (vgb+ strains) have substantially higher TPL activity than the respective wild-type hosts or the strains bearing a comparable plasmid without vgb (the vgb- strains) | Citrobacter freundii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Citrobacter freundii | - |
NRRL B-2643 | - |
Citrobacter freundii NRRL B-2643 | - |
NRRL B-2643 | - |
Pantoea agglomerans | - |
NRRL B-3466 | - |
Pantoea agglomerans NRRL B-3466 | - |
NRRL B-3466 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.017 | - |
at the 24 h culture phase, wild-type strain | Pantoea agglomerans |
0.031 | - |
at the 24 h culture phase, wild-type strain | Citrobacter freundii |
0.032 | - |
at the 12 h culture phase, wild-type strain | Citrobacter freundii |
0.058 | - |
at the 12 h culture phase, vgb- strain | Citrobacter freundii |
0.067 | - |
at the 24 h culture phase, vgb- strain | Citrobacter freundii |
0.08 | - |
at the 12 h culture phase, vgb+ strain | Citrobacter freundii |
0.098 | - |
at the 24 h culture phase, vgb- strain | Pantoea agglomerans |
0.371 | - |
at the 24 h culture phase, vgb+ strain | Citrobacter freundii |
0.513 | - |
at the 24 h culture phase, vgb+ strain | Pantoea agglomerans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
catechol + pyruvate + NH3 | TPL is well-correlated to cytoplasmic 3,4-dihydroxyphenyl-L-alanine levels | Citrobacter freundii | 3,4-dihydroxyphenyl-L-alanine | - |
r | |
catechol + pyruvate + NH3 | TPL is well-correlated to cytoplasmic 3,4-dihydroxyphenyl-L-alanine levels | Citrobacter freundii NRRL B-2643 | 3,4-dihydroxyphenyl-L-alanine | - |
r | |
L-tyrosine + H2O | TPL is well-correlated to cytoplasmic 3,4-dihydroxyphenyl-L-alanine levels | Pantoea agglomerans | 3,4-dihydroxyphenyl-L-alanine | - |
? | |
L-tyrosine + H2O | TPL is well-correlated to cytoplasmic 3,4-dihydroxyphenyl-L-alanine levels | Pantoea agglomerans NRRL B-3466 | 3,4-dihydroxyphenyl-L-alanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TPL | - |
Pantoea agglomerans |
TPL | - |
Citrobacter freundii |
tyrosine phenol-lyase | - |
Pantoea agglomerans |
tyrosine phenol-lyase | - |
Citrobacter freundii |
Organism | Comment | Expression |
---|---|---|
Pantoea agglomerans | L-tyrosine addition only has a positive effect in terms of TPL induction for cell cultures harvested after 12 h | up |
Citrobacter freundii | L-tyrosine addition only has a positive effect in terms of TPL induction for cell cultures harvested after 12 h | up |