Literature summary for 4.1.99.2 extracted from

Watkins, E.B.; Phillips, R.S.
Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine (2001), Biochemistry, 40, 14862-14868.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-aza-L-tyrosine	competitive	Citrobacter freundii
3-aza-L-tyrosine	competitive	Citrobacter freundii

Organism

Organism	UniProt	Comment	Textmining
Citrobacter freundii	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
L-tyrosine + H2O = phenol + pyruvate + NH3	mechanism	Citrobacter freundii	a

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.135	-	2-aza-L-tyrosine	25°C, pH 7.8	Citrobacter freundii
3.4	-	2-aza-L-tyrosine	25°C, pH 7.8	Citrobacter freundii

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Release 2023.1 (January 2023)