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Literature summary for 4.1.3.6 extracted from

  • Srivastava, V.; Deshpande, S.N.; Nimgaonkar, V.L.; Lerer, B.; Thelma, B.
    Genetic correlates of olanzapine-induced weight gain in schizophrenia subjects from north India: role of metabolic pathway genes (2008), Pharmacogenomics, 9, 1055-1068.
    View publication on PubMed

Application

Application Comment Organism
medicine polymorphisms of the citrate lyase gene, may be involved in appetite regulation and antipsychotic induced metabolic syndrome with olanzapine-induced weight gain, are analysed Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
citrate Homo sapiens
-
acetate + oxaloacetate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood for DNA isolation Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
citrate
-
Homo sapiens acetate + oxaloacetate
-
?

Synonyms

Synonyms Comment Organism
citrate (pro-3S)-lyase
-
Homo sapiens
citrate lyase
-
Homo sapiens