Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxobutanoate | competitive inhibition | Paraburkholderia xenovorans | |
2-oxopentanoate | competitive inhibition | Paraburkholderia xenovorans | |
4-methyl-2-oxopentanoate | competitive inhibition | Paraburkholderia xenovorans | |
glyoxylate | competitive inhibition | Paraburkholderia xenovorans | |
pyruvate | competitive inhibition | Paraburkholderia xenovorans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
14.8 | - |
pyruvate | steady-state kinetic parameter, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
64.3 | - |
acetaldehyde | app. Km-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
67 | - |
acetaldehyde | steady-state kinetic parameter, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
124.6 | - |
glycolaldehyde | app. Km-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
135.9 | - |
propionaldehyde | app. Km-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | cofactor | Paraburkholderia xenovorans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Paraburkholderia xenovorans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate + acetaldehyde | - |
Paraburkholderia xenovorans | (4S)-4-hydroxy-2-oxopentanoate | - |
? | |
pyruvate + butyraldehyde | - |
Paraburkholderia xenovorans | ? | - |
? | |
pyruvate + glycolaldehyde | - |
Paraburkholderia xenovorans | ? | - |
? | |
pyruvate + isobutyraldehyde | - |
Paraburkholderia xenovorans | ? | - |
? | |
pyruvate + pentaldehyde | - |
Paraburkholderia xenovorans | ? | - |
? | |
pyruvate + propionaldehyde | - |
Paraburkholderia xenovorans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BphI | - |
Paraburkholderia xenovorans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
glycolaldehyde | app. kcat-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.86 | - |
acetaldehyde | app. kcat-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
1.04 | - |
pyruvate | steady-state kinetic parameter, with acetaldehyde as aldehyde donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
1.79 | - |
propionaldehyde | app. kcat-value with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.21 | - |
glyoxylate | pH 8.0, 25°C | Paraburkholderia xenovorans | |
0.34 | - |
2-oxobutanoate | pH 8.0, 25°C | Paraburkholderia xenovorans | |
0.55 | - |
pyruvate | pH 8.0, 25°C | Paraburkholderia xenovorans | |
1.09 | - |
2-oxopentanoate | pH 8.0, 25°C | Paraburkholderia xenovorans | |
2.71 | - |
4-methyl-2-oxopentanoate | pH 8.0, 25°C | Paraburkholderia xenovorans | |
10.3 | - |
pyruvate | pH 8.0, 25°C | Paraburkholderia xenovorans |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00047 | - |
pentaldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.0005 | - |
Isobutyraldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.0022 | - |
Butyraldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.0037 | - |
glycolaldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.0132 | - |
propionaldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans | |
0.0134 | - |
acetaldehyde | kcat(app)/Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C | Paraburkholderia xenovorans |