Literature summary for 4.1.3.4 extracted from

Puisac, B.; Arnedo, M.; Casale, C.H.; Ribate, M.P.; Castiella, T.; Ramos, F.J.; Ribes, A.; Perez-Cerda, C.; Casals, N.; Hegardt, F.G.; Pie, J.
Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria (2010), J. Inherit. Metab. Dis., 33, 405-410.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	128.86 nmol/min/g of wet weight liver tissue, 58.49 nmol/min/g of wet weight pancreas tissue, 42.48 nmol/min/g of wet weight kidney tissue, 20.23 nmol/min/g of wet weight testis tissue, 12.6 nmol/min/g of wet weight skeletal muscle, activity not detected in heart and brain	Homo sapiens

Synonyms

Synonyms	Comment	Organism
3-hydroxy-3-methylglutaryl CoA lyase	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	3-Hydroxy-3-methylglutaric aciduria is a rare human autosomal recessive disorder caused by deficiency of 3-hydroxy-3-methylglutaryl CoA lyase	Homo sapiens

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Release 2023.1 (January 2023)