Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli JM105 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
G203E | the mutation causes 3-hydroxy-3-methylglutaric aciduria, it has less than 0.02% of the wild type enzyme activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P35914 | mitochondrial precursor | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
9.5 | - |
wild type enzyme, at 37°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-3-Hydroxy-3-methylglutaryl-CoA | - |
Homo sapiens | Acetyl-CoA + acetoacetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3-hydroxy-3-methylglutarate-CoA lyase | - |
Homo sapiens |
HMG-CoA lyase | - |
Homo sapiens |
HMGL | - |
Homo sapiens |