Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.3.1 extracted from

  • Yang, H.C.; Yu, J.; Oh, K.B.; Shin, D.S.; Cho, W.J.; Shin, J.; Kim, S.
    Synthesis and evaluation of hydroquinone derivatives as inhibitors of isocitrate lyase (2007), Arch. Pharm. Res., 30, 955-961.
    View publication on PubMed
Search for more literature for 4.1.3.1

Inhibitors

Inhibitors Comment Organism Structure
(E)-2-(3-methylnon-2-enyl)benzene-1,4-diol
-
 Candida albicans
(E)-2-(4-hydroxy-3-methylbut-2-enyl)benzene-1,4-diol
-
 Candida albicans
(E)-2-(9-hydroxy-3-methylnon-2-enyl)benzene-1,4-diol
-
 Candida albicans
2-(3-methylbut-2-enyl)benzene-1,4-diol
-
 Candida albicans
2-allylbenzene-1,4-diol
-
 Candida albicans
halisulfate 1
-
 Candida albicans
halisulfate 5
-
 Candida albicans
hydrohalisulfate 1
-
 Candida albicans
Itaconate
-
 Candida albicans

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate
-
 Candida albicans succinate + glyoxylate
-
 ?

Synonyms

Synonyms Comment Organism
ICL
-
 Candida albicans

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.06
-
-
 Candida albicans Itaconate
0.28
-
-
 Candida albicans (E)-2-(9-hydroxy-3-methylnon-2-enyl)benzene-1,4-diol
0.29
-
-
 Candida albicans (E)-2-(4-hydroxy-3-methylbut-2-enyl)benzene-1,4-diol
0.4
-
-
 Candida albicans (E)-2-(3-methylnon-2-enyl)benzene-1,4-diol
0.61
-
-
 Candida albicans 2-(3-methylbut-2-enyl)benzene-1,4-diol
1.02
-
-
 Candida albicans 2-allylbenzene-1,4-diol