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Literature summary for 4.1.2.55 extracted from

  • Lamble, H.J.; Royer, S.F.; Hough, D.W.; Danson, M.J.; Taylor, G.L.; Bull, S.D.
    A thermostable aldolase for the synthesis of 3-deoxy-2-ulosonic acids (2007), Adv. Synth. Catal., 349, 817-821.
No PubMed abstract available

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme displays a relatively broad specificity profile towards nonphosphorylated aldehydes Saccharolobus solfataricus ?
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?
pyruvate + D-erythrose formation of (4S,5S,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4S,5S,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 35:65 Saccharolobus solfataricus (4S,5S,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + D-glyceraldehyde formation of 3-deoxy-D-erythro-hex-2-ulosonate and 3-deoxy-D-threo-hex-2-ulosonate in the ratio 45:55 Saccharolobus solfataricus 3-deoxy-D-erythro-hex-2-ulosonate
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?
pyruvate + D-glyceraldehyde formation of 3-deoxy-D-erythro-hex-2-ulosonate and 3-deoxy-D-threo-hex-2-ulosonate in the ratio 45:55 Saccharolobus solfataricus 3-deoxy-D-threo-hex-2-ulosonate
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?
pyruvate + D-threose formation of (4S,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 40:60 Saccharolobus solfataricus (4R,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + D-threose formation of (4S,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 40:60 Saccharolobus solfataricus (4S,5R,6R)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + L-erythrose formation of (4S,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 60:40 Saccharolobus solfataricus (4R,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + L-erythrose formation of (4S,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 60:40 Saccharolobus solfataricus (4S,5R,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + L-glyceraldehyde formation of 3-deoxy-L-threo-hex-2-ulosonate and 3-deoxy-L-erythro-hex-2-ulosonate in the ratio 50:50 Saccharolobus solfataricus 3-deoxy-D-erythro-hex-2-ulosonate
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?
pyruvate + L-glyceraldehyde formation of 3-deoxy-L-threo-hex-2-ulosonate and 3-deoxy-L-erythro-hex-2-ulosonate in the ratio 50:50 Saccharolobus solfataricus 3-deoxy-D-threo-hex-2-ulosonate
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?
pyruvate + L-threose formation of (4S,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 90:10 Saccharolobus solfataricus (4R,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?
pyruvate + L-threose formation of (4S,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate and (4R,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate in the ratio 90:10 Saccharolobus solfataricus (4S,5S,6S)-4,5,6,7-tetrahydroxy-2-oxoheptanoate
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?

Synonyms

Synonyms Comment Organism
2-keto-3-deoxygluconate aldolase
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Saccharolobus solfataricus
KDG-aldolase
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Saccharolobus solfataricus