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Literature summary for 4.1.2.47 extracted from

  • Griengl, H.; Schwab, H.; Fechter, M.
    The synthesis of chiral cyanohydrins by oxynitrilases (2000), Trends Biotechnol., 18, 252-256.
    View publication on PubMed

Application

Application Comment Organism
agriculture enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for agrochemicals Hevea brasiliensis
agriculture enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for agrochemicals Manihot esculenta
pharmacology enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for pharmaceuticals Hevea brasiliensis
pharmacology enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for pharmaceuticals Manihot esculenta

Cloned(Commentary)

Cloned (Comment) Organism
full-length cDNA functinal expressed in Escherichia coli, Pichia pastoris and Saccharomyces cerevisiae Hevea brasiliensis

Organism

Organism UniProt Comment Textmining
Hevea brasiliensis
-
-
-
Manihot esculenta
-
cassava, Crantz
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
HCN + (2E)-oct-2-enal
-
Hevea brasiliensis (2S,3E)-2-hydroxynon-3-enenitrile
-
?
HCN + 3-furaldehyde
-
Manihot esculenta (2R)-3-furyl(hydroxy)acetonitrile
-
?
HCN + 3-phenoxybenzaldehyde
-
Hevea brasiliensis (2S)-hydroxy(3-phenoxyphenyl)acetonitrile
-
?
HCN + cyclohexanecarbaldehyde
-
Hevea brasiliensis (2R)-cyclohexyl(hydroxy)acetonitrile
-
?
HCN + phenylacetaldehyde
-
Hevea brasiliensis (2R)-2-hydroxy-3-phenylpropanenitrile
-
?

Synonyms

Synonyms Comment Organism
alpha-Hydroxynitrile lyase
-
Manihot esculenta
HNL
-
Hevea brasiliensis
HNL
-
Manihot esculenta
Hydroxynitrile lyase
-
Hevea brasiliensis
Hydroxynitrile lyase
-
Manihot esculenta
Oxynitrilase
-
Hevea brasiliensis
Oxynitrilase
-
Manihot esculenta