Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 (DE3) cells | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
micro batch method, cocrystallization of YagE with 2-keto-3-deoxy galactonate and with pyruvate and glyceraldehyde in 100 mM HEPES pH 6.5, 200 mM MgCl2, 15% (w/v) PEG 3350, 50 mM pyruvate, and 50 mM glyceraldehyde | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P75682 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydro-3-deoxy-D-galactonate | - |
Escherichia coli | ? | - |
? | |
pyruvate + glyceraldehyde | - |
Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | x-ray crystallography | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
2-keto-3-deoxy gluconate aldolase | - |
Escherichia coli |
KDG aldolase | - |
Escherichia coli |
KDGA | - |
Escherichia coli |
YagE | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of YagE increases cell viability in the presence of certain bactericidal antibiotics, indicating a putative biological role of YagE as a prophage encoded virulence factor enabling the survival of bacteria in the presence of certain antibiotics | Escherichia coli |