Application | Comment | Organism |
---|---|---|
synthesis | stereospecific formation of carbon-carbon bonds is one of the major interests in organic synthetic chemistry, aldolases are part of the most important group of asymmetric C-C-bonding enzymes | Saccharolobus solfataricus |
synthesis | stereospecific formation of carbon-carbon bonds is one of the major interests in organic synthetic chemistry, aldolases are part of the most important group of asymmetric C-C-bonding enzymes | Thermoproteus tenax |
Cloned (Comment) | Organism |
---|---|
using the pET expression system | Saccharolobus solfataricus |
using the pET expression system | Thermoproteus tenax |
Crystallization (Comment) | Organism |
---|---|
the crystal structure of the apoprotein is determined to a resolution of 2.0 A, the structure of the protein covalently linked to pyruvate is determined to 2.2 A | Thermoproteus tenax |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
- |
Thermoproteus tenax |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydro-3-deoxy-6-phospho-D-gluconate | Saccharolobus solfataricus | - |
pyruvate + D-glyceraldehyde 3-phosphate | - |
r | |
2-dehydro-3-deoxy-6-phospho-D-gluconate | Thermoproteus tenax | - |
pyruvate + D-glyceraldehyde 3-phosphate | - |
r | |
2-dehydro-3-deoxy-D-galactonate | Saccharolobus solfataricus | - |
pyruvate + D-glyceraldehyde | - |
? | |
2-dehydro-3-deoxy-D-gluconate | Saccharolobus solfataricus | - |
pyruvate + D-glyceraldehyde | - |
r | |
2-dehydro-3-deoxy-D-gluconate | Thermoproteus tenax | - |
pyruvate + D-glyceraldehyde | - |
r | |
2-keto-3-deoxy-6-phosphogalactonate | Saccharolobus solfataricus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharolobus solfataricus | - |
- |
- |
Thermoproteus tenax | Q704D1 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharolobus solfataricus |
- |
Thermoproteus tenax |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydro-3-deoxy-6-phospho-D-gluconate | - |
Saccharolobus solfataricus | pyruvate + D-glyceraldehyde 3-phosphate | - |
r | |
2-dehydro-3-deoxy-6-phospho-D-gluconate | - |
Thermoproteus tenax | pyruvate + D-glyceraldehyde 3-phosphate | - |
r | |
2-dehydro-3-deoxy-D-galactonate | - |
Saccharolobus solfataricus | pyruvate + D-glyceraldehyde | - |
? | |
2-dehydro-3-deoxy-D-gluconate | - |
Saccharolobus solfataricus | pyruvate + D-glyceraldehyde | - |
r | |
2-dehydro-3-deoxy-D-gluconate | - |
Thermoproteus tenax | pyruvate + D-glyceraldehyde | - |
r | |
2-keto-3-deoxy-6-phosphogalactonate | - |
Saccharolobus solfataricus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
2-keto-3-deoxy-(6-phospho)-gluconate aldolase | - |
Saccharolobus solfataricus |
2-keto-3-deoxy-(6-phospho)-gluconate aldolase | - |
Thermoproteus tenax |
KD(P)G aldolase | - |
Saccharolobus solfataricus |
KD(P)G aldolase | - |
Thermoproteus tenax |