Application | Comment | Organism |
---|---|---|
medicine | 2-keto-3-deoxy-6-phosphogluconate aldolase is an attractive target for drug therapy in the case of human Streptococcus suis infections | Streptococcus suis |
Cloned (Comment) | Organism |
---|---|
into the vector pET21a for expression in Escherichia coli BL21DE3 cells | Streptococcus suis |
Crystallization (Comment) | Organism |
---|---|
the structure of 2-keto-3-deoxy-6-phosphogluconate aldolase is solved at a resolution of 2.8 A | Streptococcus suis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
22920 | - |
calculated | Streptococcus suis |
23000 | - |
determined by SDS-PAGE | Streptococcus suis |
60000 | - |
determined by gel filtration, trimer | Streptococcus suis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydro-3-deoxy-D-gluconate 6-phosphate | Streptococcus suis | - |
pyruvate + D-glyceraldehyde 3-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus suis | A4VVI7 | serotype 2 | - |
Purification (Comment) | Organism |
---|---|
using a nickel-affinity and a Superdex 200 column | Streptococcus suis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydro-3-deoxy-D-gluconate 6-phosphate | - |
Streptococcus suis | pyruvate + D-glyceraldehyde 3-phosphate | - |
r |
Subunits | Comment | Organism |
---|---|---|
homotrimer | - |
Streptococcus suis |
Synonyms | Comment | Organism |
---|---|---|
2-keto-3-deoxy-6-phosphogluconate aldolase | - |
Streptococcus suis |
KDPG aldolase | - |
Streptococcus suis |