Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Mycobacterium tuberculosis |
expressed in Escherichia coli | Candida albicans |
expressed in Escherichia coli | Helicobacter pylori |
expressed in Escherichia coli | Yersinia pestis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | - |
Candida albicans | |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | - |
Helicobacter pylori | |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | - |
Mycobacterium tuberculosis | |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | - |
Oryctolagus cuniculus | |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | - |
Yersinia pestis | |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Candida albicans | |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Helicobacter pylori | |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Mycobacterium tuberculosis | |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Oryctolagus cuniculus | |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Yersinia pestis | |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Candida albicans | |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Helicobacter pylori | |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Mycobacterium tuberculosis | |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Oryctolagus cuniculus | |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | - |
Yersinia pestis | |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | - |
Candida albicans | |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | - |
Helicobacter pylori | |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | - |
Mycobacterium tuberculosis | |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | - |
Oryctolagus cuniculus | |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | - |
Yersinia pestis | |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | - |
Candida albicans | |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | - |
Helicobacter pylori | |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | - |
Mycobacterium tuberculosis | |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | - |
Oryctolagus cuniculus | |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | - |
Yersinia pestis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | dependent on | Mycobacterium tuberculosis | |
Zn2+ | dependent on | Candida albicans | |
Zn2+ | dependent on | Helicobacter pylori | |
Zn2+ | dependent on | Yersinia pestis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Helicobacter pylori | - |
- |
- |
Mycobacterium tuberculosis | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Yersinia pestis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | - |
Oryctolagus cuniculus | dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Mycobacterium tuberculosis | dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Candida albicans | dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Helicobacter pylori | dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Yersinia pestis | dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
sedoheptulose 1,7-bis-phosphate | - |
Mycobacterium tuberculosis | ? | - |
? | |
sedoheptulose 1,7-bis-phosphate | - |
Oryctolagus cuniculus | glycerone phosphate + D-erythrose 4-phosphate | - |
? | |
sedoheptulose 1,7-bis-phosphate | - |
Candida albicans | glycerone phosphate + D-erythrose 4-phosphate | - |
? | |
sedoheptulose 1,7-bis-phosphate | - |
Helicobacter pylori | glycerone phosphate + D-erythrose 4-phosphate | - |
? | |
sedoheptulose 1,7-bis-phosphate | - |
Yersinia pestis | glycerone phosphate + D-erythrose 4-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
class I Fba | - |
Oryctolagus cuniculus |
class II FBA | - |
Mycobacterium tuberculosis |
class II FBA | - |
Candida albicans |
class II FBA | - |
Helicobacter pylori |
class II FBA | - |
Yersinia pestis |
FBA | - |
Oryctolagus cuniculus |
FBA | - |
Mycobacterium tuberculosis |
FBA | - |
Candida albicans |
FBA | - |
Helicobacter pylori |
FBA | - |
Yersinia pestis |
fructose bis-phosphate aldolase | - |
Oryctolagus cuniculus |
fructose bis-phosphate aldolase | - |
Mycobacterium tuberculosis |
fructose bis-phosphate aldolase | - |
Candida albicans |
fructose bis-phosphate aldolase | - |
Helicobacter pylori |
fructose bis-phosphate aldolase | - |
Yersinia pestis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000013 | - |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Mycobacterium tuberculosis | |
0.000013 | - |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Helicobacter pylori | |
0.00012 | - |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Mycobacterium tuberculosis | |
0.00017 | - |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Mycobacterium tuberculosis | |
0.000185 | - |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Mycobacterium tuberculosis | |
0.000195 | - |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Yersinia pestis | |
0.000195 | - |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Yersinia pestis | |
0.0002 | - |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Candida albicans | |
0.000234 | - |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Yersinia pestis | |
0.00028 | - |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Candida albicans | |
0.0003 | - |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Candida albicans | |
0.00031 | - |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Mycobacterium tuberculosis | |
0.000416 | - |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Candida albicans | |
0.0008 | - |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Candida albicans | |
0.001 | - |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Helicobacter pylori | |
0.004 | - |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Helicobacter pylori | |
0.0047 | - |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Helicobacter pylori | |
0.0055 | - |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Helicobacter pylori | |
0.067 | - |
2-(3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)ethyl phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Oryctolagus cuniculus | |
0.264 | - |
3-[hydroxy[(phosphonooxy)acetyl]amino]propyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Oryctolagus cuniculus | |
0.4 | - |
2-[hydroxy(4-hydroxybutyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Oryctolagus cuniculus | |
0.85 | - |
4-[hydroxy[(phosphonooxy)acetyl]amino]butyl hexanoate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Oryctolagus cuniculus | |
2.5 | - |
2-[hydroxy(3-hydroxypropyl)amino]-2-oxoethyl dihydrogen phosphate | in glycyl-glycine buffer (0.1 M pH 7.4), temperature not specified in the publication | Oryctolagus cuniculus |