Literature summary for 4.1.1.7 extracted from

Bera, A.K.; Polovnikova, L.S.; Roestamadji, J.; Widlanski, T.S.; Kenyon, G.L.; McLeish, M.J.; Hasson, M.S.
Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme (2007), J. Am. Chem. Soc., 129, 4120-4121.

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Inhibitors

Inhibitors	Comment	Organism	Structure
acetylphosphonate	-	Pseudomonas putida
benzoylphosphonate	competitive inhibitor	Pseudomonas putida
methyl acetylphosphonate	-	Pseudomonas putida

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	P20906	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzoylformate	-	Pseudomonas putida	benzaldehyde + CO2	-	?

Synonyms

Synonyms	Comment	Organism
BFD	-	Pseudomonas putida

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	dependent	Pseudomonas putida

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.36	-	benzoylphosphonate	prolonged incubation of BFD with benzoylphosphonate results in permanent inactivation of the enzyme	Pseudomonas putida

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Release 2023.1 (January 2023)