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Literature summary for 4.1.1.50 extracted from

  • Hyvoenen, M.T.; Howard, M.T.; Anderson, C.B.; Grigorenko, N.; Khomutov, A.R.; Vepsaelaeinen, J.; Alhonen, L.; Jaenne, J.; Keinaenen, T.A.
    Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues (2009), Biochem. J., 422, 321-328.
    View publication on PubMed
Search for more literature for 4.1.1.50

Activating Compound

Activating Compound Comment Organism Structure
difluoromethylornithine 5 mM causes an induction of the enzyme activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
(R)-alpha-methylspermine
-
 Homo sapiens
(R,R)-alpha,omega-bismethylspermine best suppressor of AdoMetDC activity Homo sapiens
(S)-alpha-methylspermidine
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine
-
 Homo sapiens (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

Synonyms

Synonyms Comment Organism
AdoMetDC
-
 Homo sapiens
S-Adenosyl-L-methionine decarboxylase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Homo sapiens