Literature summary for 4.1.1.50 extracted from

Kinch, L.N.; Phillips, M.A.
Single-turnover kinetic analysis of Trypanosoma cruzi S-adenosylmethionine decarboxylase (2000), Biochemistry, 39, 3336-3343.

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Protein Variants

Protein Variants	Comment	Organism
C82A	drastically reduced single turnover rate, no solvent isotope effect, C82 may function as a general aci/base in catalysis	Trypanosoma cruzi

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma cruzi	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
S-adenosyl-L-methionine = S-adenosyl 3-(methylsulfanyl)propylamine + CO2	kinetic analysis, inverse solvent isotope effect	Trypanosoma cruzi	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine	-	Trypanosoma cruzi	(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
6	-	S-adenosyl-methionine	in presence of putrescine	Trypanosoma cruzi

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Release 2023.1 (January 2023)