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Literature summary for 4.1.1.49 extracted from

  • Urbina, J.A.; Orsono, C.E.; Rojas, A.
    Inhibition of phosphoenolpyruvate carboxykinase from Trypanosoma (Schizotrypanum) cruzi epimastigotes by 3-mercaptopicolinic acid: in vitro and in vivo studies (1990), Arch. Biochem. Biophys., 282, 91-99.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
3-Mercaptopicolinic acid specific to this enzyme Trypanosoma cruzi

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ strictly dependent on Trypanosoma cruzi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Trypanosoma cruzi central role in energy metabolism ?
-
 ?
additional information Trypanosoma cruzi important regulatory function of the enzyme in the amino-acid catabolism of Trypanosoma cruzi ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epimastigote
-
 Trypanosoma cruzi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphoenolpyruvate + CO2
-
 Trypanosoma cruzi ATP + oxaloacetate
-
 ?
additional information central role in energy metabolism Trypanosoma cruzi ?
-
 ?
additional information important regulatory function of the enzyme in the amino-acid catabolism of Trypanosoma cruzi Trypanosoma cruzi ?
-
 ?