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Literature summary for 4.1.1.48 extracted from

  • Hennig, M.; Darimont, B.D.; Jansonius, J.N.; Kirschner, K.
    The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product (2002), J. Mol. Biol., 319, 757-766.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with substrate 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate, with a substrate analogue, and with product indole-3-glycerol phosphate Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q06121
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Reaction

Reaction Comment Organism Reaction ID
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O mechanism, structures of two putative catalytic intermediates Saccharolobus solfataricus