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Literature summary for 4.1.1.36 extracted from

  • Scandurra, R.; Barboni, E.; Granata, F.; Pensa, B.; Costa, M.
    Pantothenoylcysteine-4'-phosphate decarboxylase from horse liver (1974), Eur. J. Biochem., 49, 1-9.
    View publication on PubMed
Search for more literature for 4.1.1.36

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol increases activity Equus caballus
cysteine
-
 Rattus norvegicus
cysteine increases activity Equus caballus
DTT increases activity Equus caballus

Inhibitors

Inhibitors Comment Organism Structure
4,4-Bis(dimethylaminodiphenylcarbinol)
-
 Rattus norvegicus
hydroxylamine
-
 Equus caballus
iodoacetamide
-
 Equus caballus
NaBH4
-
 Equus caballus
phenylhydrazine
-
 Equus caballus
pyridoxal 5'-phosphate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.43
-
 4-phosphopantothenoyl-L-Cys
-
 Equus caballus

Localization

Localization Comment Organism GeneOntology No. Textmining
intracellular not bound to any cellular structure Equus caballus 5622
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Equus caballus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Equus caballus

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Sus scrofa
-
heart
-
 Bos taurus
-
heart
-
 Equus caballus
-
kidney
-
 Rattus norvegicus
-
kidney
-
 Sus scrofa
-
kidney
-
 Bos taurus
-
kidney
-
 Oryctolagus cuniculus
-
kidney
-
 Equus caballus
-
liver
-
 Rattus norvegicus
-
liver
-
 Sus scrofa
-
liver
-
 Bos taurus
-
liver
-
 Oryctolagus cuniculus
-
liver
-
 Equus caballus
-
muscle
-
 Sus scrofa
-
muscle
-
 Bos taurus
-
muscle
-
 Equus caballus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.089
-
-
 Equus caballus

Storage Stability

Storage Stability Organism
stable for at least 2 months if frozen as diluted solution, less than 1 mg/ml, or concentrated solution, 1-10 mg/ml Equus caballus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Rattus norvegicus Pantotheine 4-phosphate + CO2
-
 ?
N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Sus scrofa Pantotheine 4-phosphate + CO2
-
 ?
N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Bos taurus Pantotheine 4-phosphate + CO2
-
 ?
N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Oryctolagus cuniculus Pantotheine 4-phosphate + CO2
-
 ?
N-((R)-4-Phosphopantothenoyl)-L-Cys specific for Equus caballus Pantotheine 4-phosphate + CO2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
-
 Equus caballus

pH Range

pH Minimum pH Maximum Comment Organism
6 9.5 pH 9.5: 75% of optimal activity, pH 6: 23% of optimal activity Equus caballus