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Literature summary for 4.1.1.33 extracted from

  • Jabalquinto, A.M.; Cardemil, E.
    The effect of diabetes, nutritional factors, and sex on rat liver and kidney mevalonate kinase, mevalonate-5-phosphate kinase, and mevalonate-5-pyrophosphate decarboxylase (1981), Arch. Biochem. Biophys., 210, 132-139.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
kidney in female rat the activity is lower than in male rat Rattus norvegicus
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liver in female rats the activity is higher than in male animals Rattus norvegicus
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liver decrease in activity when rats are fasted, fed with a diet containing 2% cholesterol or made diabetic, increase in activity when the animals are fed with a diet containing 3% cholestyramine Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5-diphosphomevalonate
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Rattus norvegicus ADP + phosphate + isopentenyl diphosphate + CO2
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