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Literature summary for 4.1.1.32 extracted from
- Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes (2008), J. Nutr., 138, 1004-1009.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | all-trans-retinoic acid is a transcriptional inducer of the PEPCK-C gene. 9-cis-retinoic acid and all-trans-retinoic acid stimulate PEPCK-C expression in 3T3-442A adipocytes | Rattus norvegicus | |
| additional information | all-trans-retinoic acid is a transcriptional inducer of the PEPCK-C gene. 9-cis-retinoic acid and all-trans-retinoic acid stimulate PEPCK-C expression in 3T3-442A adipocytes | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P35558 | women, aged 45.7 +/- 4.4 years and have body mass index of 30.3 +/- 1.4 kg m-2 | - |
| Rattus norvegicus | - |
six-week-old male Sprague-Dawley rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| 3T3-442A cell | - |
Rattus norvegicus | - |
| adipocyte | rodent adipocyte | Rattus norvegicus | - |
| white adipose tissue | WAT | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDC-E2 | - |
Rattus norvegicus |
| PEPCK-C | - |
Homo sapiens |
| phosphoenolpyruvate carboxykinase | - |
Rattus norvegicus |
| phosphoenolpyruvate carboxykinase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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