Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | high expression of DDC in blood and bone marrow corresponds to metastatic neuroblastoma at diagnosis, residual disease, and poor outcome | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | diagnosis of neuroblastoma, both tyrosine hydroxylase mRNA and DDC mRNA could be useful for stratifying patients into different treatment groups in future clinical trials. | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Dopa | Homo sapiens | - |
dopamine + CO2 | - |
? | |
additional information | Homo sapiens | tyrosine hydroxylase mRNA and DDC mRNA in plasma of children with neuroblastoma are highly correlated | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | from children with neuroblastoma | Homo sapiens | - |
bone marrow | rom the posterior iliac crest of children with neuroblastoma | Homo sapiens | - |
neuroblastoma cell line | IMR 32, CHP-212, SH-SY5Y, SK-N-SH, SK-N-FI, SK-N-AS, SK-N-BE(2) and SK-N-DZ | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Dopa | - |
Homo sapiens | dopamine + CO2 | - |
? | |
additional information | tyrosine hydroxylase mRNA and DDC mRNA in plasma of children with neuroblastoma are highly correlated | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DDC | - |
Homo sapiens |
DOPA decarboxylase | - |
Homo sapiens |