Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.28 extracted from

  • Srinivasan, K.; Awapara, J.
    Substrate specificity and other properties of dopa decarboxylase from guinea pig kidneys (1978), Biochim. Biophys. Acta, 526, 597-604.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
BH4
-
Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Cavia porcellus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
23.27
-
-
Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-Dihydroxyphenylalanine
-
Cavia porcellus 3-Hydroxytyramine + CO2
-
?
5-Hydroxytryptophan
-
Cavia porcellus Serotonin + CO2
-
?
His no activity Cavia porcellus ?
-
?
L-Phe no reaction Cavia porcellus phenylethylamine + CO2
-
?
m-Tyr
-
Cavia porcellus ?
-
?
additional information no activity with 3-methoxyphenylalanine Cavia porcellus ?
-
?
o-Tyr
-
Cavia porcellus ?
-
?
Tyr no activity with L-Tyr Cavia porcellus ?
-
?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate addition of pyridoxal 5'-phosphate increases activity towards 3,4-dihydroxyphenylalanine, o-Tyr, m-Tyr, but not towards 5-hydroxytryptophan Cavia porcellus