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Literature summary for 4.1.1.22 extracted from
- Substrate uptake and protein stability relationship in mammalian histidine decarboxylase (2010), Proteins, 78, 154-161.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-Fluoromethylhistidine | - |
Mus musculus |  |
| Histidine methyl ester | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidine | - |
Mus musculus | histamine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HDC | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mus musculus | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme and its product, histamine, are involved in multiple inflammatory diseases, atherosclerosis, some neurological and neuroendocrine diseases, osteroporosis, fertility, and several types of neoplasia | Mus musculus |
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Release 2023.1 (January 2023)
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