Literature summary for 4.1.1.22 extracted from

Varkonyi, J.; Karadi, I.; Szocs, K.; Sugar, I.; Sapi, Z.; Marschalko, M.; Pallinger, E.; Darvas, Z.; Falus, A.
Loss of histidine decarboxylase as a marker of malignant transformation and dedifferentiation of B-cells infiltrating the skin. A case report of a therapy-resistant multiple myeloma complicated by skin infiltration (2008), Acta Oncol., 47, 458-461.

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Application

Application	Comment	Organism
medicine	loss of HDC is a marker of malignant transformation and dedifferentiation of B-cells infiltrating the skin	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
B-lymphocyte	-	Homo sapiens	-
bone marrow	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-histidine	-	Homo sapiens	histamine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
HDC	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Homo sapiens

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Release 2023.1 (January 2023)