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Literature summary for 4.1.1.22 extracted from

  • Landete, J.M.; Pardo, I.; Ferrer, S.
    Histamine, histidine, and growth-phase mediated regulation of the histidine decarboxylase gene in lactic acid bacteria isolated from wine (2006), FEMS Microbiol. Lett., 260, 84-90.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Oenococcus oeni
additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Lentilactobacillus hilgardii
additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Pediococcus parvulus
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Oenococcus oeni
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Lentilactobacillus hilgardii
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Pediococcus parvulus

Inhibitors

Inhibitors Comment Organism Structure
additional information histamine causes a decrease in the expression of gene hdc Lentilactobacillus hilgardii
additional information histamine causes a decrease in the expression of gene hdc Oenococcus oeni
additional information histamine causes a decrease in the expression of gene hdc Pediococcus parvulus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-histidine Oenococcus oeni expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?
L-histidine Lentilactobacillus hilgardii expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?
L-histidine Pediococcus parvulus expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?
L-histidine Pediococcus parvulus P270 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?
L-histidine Lentilactobacillus hilgardii 464 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?
L-histidine Oenococcus oeni 4042 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
?

Organism

Organism UniProt Comment Textmining
Lentilactobacillus hilgardii
-
isolated from wine, gene hdc
-
Lentilactobacillus hilgardii 464
-
isolated from wine, gene hdc
-
Oenococcus oeni
-
isolated from wine, gene hdc
-
Oenococcus oeni 4042
-
isolated from wine, gene hdc
-
Pediococcus parvulus
-
isolated from wine, gene hdc
-
Pediococcus parvulus P270
-
isolated from wine, gene hdc
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Lentilactobacillus hilgardii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-histidine
-
Oenococcus oeni histamine + CO2
-
?
L-histidine
-
Lentilactobacillus hilgardii histamine + CO2
-
?
L-histidine
-
Pediococcus parvulus histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Oenococcus oeni histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Lentilactobacillus hilgardii histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Pediococcus parvulus histamine + CO2
-
?
L-histidine
-
Pediococcus parvulus P270 histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Pediococcus parvulus P270 histamine + CO2
-
?
L-histidine
-
Lentilactobacillus hilgardii 464 histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Lentilactobacillus hilgardii 464 histamine + CO2
-
?
L-histidine
-
Oenococcus oeni 4042 histamine + CO2
-
?
L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Oenococcus oeni 4042 histamine + CO2
-
?

Synonyms

Synonyms Comment Organism
HDC
-
Oenococcus oeni
HDC
-
Lentilactobacillus hilgardii
HDC
-
Pediococcus parvulus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Oenococcus oeni
37
-
assay at Lentilactobacillus hilgardii
37
-
assay at Pediococcus parvulus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.8
-
assay at Oenococcus oeni
4.8
-
assay at Lentilactobacillus hilgardii
4.8
-
assay at Pediococcus parvulus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Oenococcus oeni
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Lentilactobacillus hilgardii
pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Pediococcus parvulus