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Literature summary for 4.1.1.22 extracted from

  • Coton, E.; Rollan, G.C.; Lonvaud-Funel, A.
    Histidine carboxylase of Leuconostoc oenos 9204: purification, kinetic properties, cloning and nucleotide sequence of the hdc gene (1998), J. Appl. Microbiol., 84, 143-151.
    View publication on PubMed
Search for more literature for 4.1.1.22

Cloned(Commentary)

Cloned (Comment) Organism
-
 Oenococcus oeni

Inhibitors

Inhibitors Comment Organism Structure
histamine
-
 Clostridium perfringens
histamine
-
 Oenococcus oeni

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.33
-
 L-His
-
 Oenococcus oeni

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
8840
-
 6 * 25380, alpha, + 6 * 8840, beta, synthesized as a precursor proHDC pi6 of MW 205000. A cleavage between Ser81 and Ser82 generates the alpha and beta chains, calculation from nucleotide sequence Oenococcus oeni
25380
-
 6 * 25380, alpha, + 6 * 8840, beta, synthesized as a precursor proHDC pi6 of MW 205000. A cleavage between Ser81 and Ser82 generates the alpha and beta chains, calculation from nucleotide sequence Oenococcus oeni

Organism

Organism UniProt Comment Textmining
Clostridium perfringens
-
-
-
Lactobacillus sp.
-
-
-
Lentilactobacillus buchneri
-
-
-
Micrococcus sp.
-
-
-
Oenococcus oeni
-
-
-
Oenococcus oeni 9204
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Oenococcus oeni

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
17.26
-
-
 Oenococcus oeni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-His
-
 Lactobacillus sp. Histamine + CO2
-
 ?
L-His
-
 Lentilactobacillus buchneri Histamine + CO2
-
 ?
L-His
-
 Clostridium perfringens Histamine + CO2
-
 ?
L-His
-
 Micrococcus sp. Histamine + CO2
-
 ?
L-His
-
 Oenococcus oeni Histamine + CO2
-
 ?
L-His
-
 Oenococcus oeni 9204 Histamine + CO2
-
 ?

Subunits

Subunits Comment Organism
hexamer 6 * 25380, alpha, + 6 * 8840, beta, synthesized as a precursor proHDC pi6 of MW 205000. A cleavage between Ser81 and Ser82 generates the alpha and beta chains, calculation from nucleotide sequence Oenococcus oeni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.8
-
-
 Lactobacillus sp.
4.8
-
-
 Oenococcus oeni