Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.22 extracted from

  • Kamath, A.V.; Vaaler, G.L.; Snell, E.E.
    Pyridoxal phosphate-dependent histidine decarboxylases: Cloning, sequencing, and expression of genes from Klebsiella planticola and Enterobacter aerogenes and properties of the overexpressed enzymes (1991), J. Biol. Chem., 266, 9432-9437.
    View publication on PubMed
Search for more literature for 4.1.1.22

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Klebsiella aerogenes
expression in Escherichia coli Raoultella planticola

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5
-
 L-His
-
 Raoultella planticola
2.6
-
 L-His
-
 Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-
Raoultella planticola
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
80.5
-
-
 Raoultella planticola
153
-
-
 Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-His
-
 Klebsiella aerogenes Histamine + CO2
-
 ?
L-His
-
 Raoultella planticola Histamine + CO2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Klebsiella aerogenes
6.5
-
-
 Raoultella planticola

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate contains 1 mol of pyridoxal 5'-phosphate per mol of subunit Klebsiella aerogenes
pyridoxal 5'-phosphate contains 1 mol of pyridoxal 5'-phosphate per mol of subunit Raoultella planticola